ABSTRACT
Transthoracic CT-guided percutaneous fine-needle aspiration biopsy [FNAB] has become a well- established diagnostic technique and been useful in differentiating malignant and benign pulmonary lesions. 505 patients [311 men and 194 women] aged 7-90 years old [mean age 56.2 years] with pulmonary lesions underwent CT-guided transthoracic fine-needle aspiration biopsy. Cytopathologic evaluation of FNAB samples was performed in all patients. In addition, each case was reviewed for complications, including pneumothorax and hemoptysis. Data were analysed using SPSS software for windows ver. 11.5. FNAB samples were adequate for diagnosis in 410 [81.2%] of 505 patients. Two hundred and forty-nine lesions [60.7%0] were malignant, and 161 [39.3%] were benign or atypical. Thirty-four [6.7%] patients had pneumothorax out of which none of them required thoracostomy tube placement. Additionally, hemoptysis was noted in 9 [1.8%] patients and follow-up was carried out. No further complications were reported. CT-guided FNAB of pulmonary lesions can yield well-established diagnoses and it can be useful in the management of patients with suspected lung cancer
Subject(s)
Humans , Male , Female , Child , Adolescent , Adult , Middle Aged , Aged , Biopsy, Fine-Needle , Tomography, X-Ray Computed , Lung Neoplasms/diagnosis , Pneumothorax , HemoptysisABSTRACT
Angiomyolipoma [AML] is uncommon outside the kidney, and it rarely occurs in mediastinum. This article presents a case of posterior upper mediastinal AML with a review of the literature on angiomyolipoma. A 56-year-old woman was referred to our hospital with 8-month history of cough and chest pain. Radiology showed a mass in the posterior upper mediastinum. Left thoracotomy was done for surgical removal of the tumor. Pathologic findings revealed an AML tumor in the left paravertebral and posterior upper mediastinal regions with massive infiltration of the intercostal nerves and subtle invasion of the adjacent thoracic spinal canal. This case is the third reported AML of posterior upper mediastinum. To prevent misdiagnosis, it is suggested that AML could be considered for the differential diagnosis of mediastinal tumors
Subject(s)
Humans , Female , Mediastinal Neoplasms/pathology , Review , Angiomyolipoma/surgery , Tomography, X-Ray ComputedABSTRACT
Pulmonary carcinoid tumor is a low-grade malignant neoplasm comprised of neuroendocrine cells. The aim of this study was to determine the clinical features; radiological and bronchoscopic findings, as well as treatment in patients. Material and Method: The hospital records of 21 patients with pulmonary carciniod tumor, who admitted to NRITLD between 1995 and 2001, were evaluated. 19 patients had typical and 2 had atypical carcinoid tumor. Male to female ratio was 1.1. The mean age = SD was 39.33 = 16.31.Cough [80.9%] was the most common presenting symptom. 16 patients had abnormal chest radiography. The diagnosis was made using bronchoscopy and biopsy. Most of the tumors arose in main bronchi. Surgery with or without endobronchial laser therapy was the treatment of our patients. Lobectomy [47.3%] was the most common procedure.surgery with or without laser therapy has a favorable outcome in pulmonary carcinoid tumors
Subject(s)
Humans , Male , Female , Lung Neoplasms/pathology , Carcinoid Tumor/surgery , Bronchoscopy , Retrospective StudiesABSTRACT
Langerhans cell histiocytosis [LCH] is a disease of unknown etiology that presents in three forms: Letterer- Siwe disease, Hand-Schuller-Christian disease, and Eosinophilic Granuloma. It is a multifocal disease that usually affects several organs and unifocal forms are rare. Pulmonary involvement occurs in approximately 40% of cases and almost always in young adults. Lungs are rarely affected in infant patients. This report presents a 15-month-old male infant that was admitted for cyanosis and respiratory distress. Diagnostic work up revealed a primary pulmonary histiocytosis and the treatment made a significant improvement of signs and symptoms by the time of discharge